Nucleic acid changes during photodynamic inactivation of bacteria by cationic porphyrins

Light activation of photosensitizing dyes in presence of molecular oxygen generates highly cytotoxic reactive oxygen species leading to cell inactivation. Nucleic acids are molecular targets of this photodynamic action but not considered the main cause of cell death. The in vivo effect of the photod...

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Detalhes bibliográficos
Autor principal: Alves, Eliana (author)
Outros Autores: Faustino, Maria A. F. (author), Tomé, João P. C. (author), Neves, Maria G. P. M. S. (author), Tomé, Augusto C. (author), Cavaleiro, José A. S. (author), Cunha, Ângela (author), Gomes, Newton C. M. (author), Almeida, Adelaide (author)
Formato: article
Idioma:eng
Publicado em: 2019
Assuntos:
Texto completo:http://hdl.handle.net/10773/25620
País:Portugal
Oai:oai:ria.ua.pt:10773/25620