WNK2 Inhibits Autophagic Flux in Human Glioblastoma Cell Line

Autophagy is a cell-survival pathway with dual role in tumorigenesis, promoting either tumor survival or tumor death. WNK2 gene, a member of the WNK (with no lysine (K)) subfamily, acts as a tumor suppressor gene in gliomas, regulating cell migration and invasion; however, its role in autophagy proc...

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Bibliographic Details
Main Author: Alves, Ana Laura Vieira (author)
Other Authors: Costa, Angela Margarida (author), Martinho, Olga (author), da Silva, Vinicius Duval (author), Jordan, Peter (author), Silva, Viviane Aline Oliveira (author), Reis, Rui Manuel (author)
Format: article
Language:eng
Published: 2021
Subjects:
WNK2
WNK Protein Kinase
Autophagy
Autophagic Flux
Glioblastoma Cell Line
Inhibition
Glioma
Vias de Transdução de Sinal e Patologias Associadas
Online Access:http://hdl.handle.net/10400.18/7344
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/7344

Internet

http://hdl.handle.net/10400.18/7344

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