Biophysical and biological properties of atypical sphingolipids : implications to physiology and pathophysiology
1-deoxy-sphingolipids lack the C1-OH on their sphingoid base and present a cis ∆14-15 double bond instead of the canonical trans ∆4-5 double bond. Increased 1-deoxy-sphingolipid levels are directly correlated with the development and progression of hereditary sensory and autonomic neuropathy type 1...
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| Formato: | doctoralThesis |
| Idioma: | eng |
| Publicado em: |
2021
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| Texto completo: | http://hdl.handle.net/10451/50380 |
| País: | Portugal |
| Oai: | oai:repositorio.ul.pt:10451/50380 |