Biophysical and biological properties of atypical sphingolipids : implications to physiology and pathophysiology

1-deoxy-sphingolipids lack the C1-OH on their sphingoid base and present a cis ∆14-15 double bond instead of the canonical trans ∆4-5 double bond. Increased 1-deoxy-sphingolipid levels are directly correlated with the development and progression of hereditary sensory and autonomic neuropathy type 1...

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Bibliographic Details
Main Author: Da Cunha Branco Dos Santos, Tânia (author)
Format: doctoralThesis
Language:eng
Published: 2021
Subjects:
Online Access:http://hdl.handle.net/10451/50380
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/50380