Biophysical and biological properties of atypical sphingolipids : implications to physiology and pathophysiology
1-deoxy-sphingolipids lack the C1-OH on their sphingoid base and present a cis ∆14-15 double bond instead of the canonical trans ∆4-5 double bond. Increased 1-deoxy-sphingolipid levels are directly correlated with the development and progression of hereditary sensory and autonomic neuropathy type 1...
Main Author: | |
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Format: | doctoralThesis |
Language: | eng |
Published: |
2021
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Subjects: | |
Online Access: | http://hdl.handle.net/10451/50380 |
Country: | Portugal |
Oai: | oai:repositorio.ul.pt:10451/50380 |