Synonymous substitution rates predict HIV disease progression as a result of underlying replication dynamics

Upon HIV transmission, some patients develop AIDS in only a few months, while others remain disease free for 20 or more years. This variation in the rate of disease progression is poorly understood and has been attributed to host genetics, host immune res

Bibliographic Details
Main Author: Lemey, Philippe (author)
Other Authors: Kosakovsky Pond, Sergei L. (author), Drummond, Alexei J. (author), Pybus, Oliver G. (author), Shapiro, Beth (author), Barroso, Helena (author), Taveira, Nuno (author), Rambaut, Andrew (author)
Format: article
Language:eng
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10451/21395
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21395