Modelling aptamers with nucleic acid mimics (NAM): from sequence to three-dimensional docking

Aptamers are single-stranded oligonucleotides, formerly evolved by Systematic Evolution of Ligands by EXponential enrichment (SELEX), that fold into functional three-dimensional structures. Such conformation is crucial for aptamers ability to bind to a target with high affinity and specificity. Unna...

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Bibliographic Details
Main Author: Oliveira, Ricardo (author)
Other Authors: Pinho, Eva (author), Sousa, Ana Luísa (author), Dias, Oscar (author), Azevedo, Nuno Filipe (author), Almeida, Carina Manuela Fernandes (author)
Format: article
Language:eng
Published: 2022
Subjects:
Science & Technology
Online Access:https://hdl.handle.net/1822/76691
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/76691

Internet

https://hdl.handle.net/1822/76691

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