4-Hydroxytamoxifen is a potent inhibitor of the mitochondrial permeability transition
The effects of 4-hydroxytamoxifen (OHTAM), the major active metabolite of the antiestrogen tamoxifen used in the breast cancer therapy, were studied on the mitochondrial permeability transition (MPT) and bioenergetic functions of mitochondria to evaluate the mechanisms underlying the cell death and...
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| Outros Autores: | , |
| Formato: | article |
| Idioma: | eng |
| Publicado em: |
2002
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| Assuntos: | |
| Texto completo: | http://hdl.handle.net/10316/5789 |
| País: | Portugal |
| Oai: | oai:estudogeral.sib.uc.pt:10316/5789 |