(R,R)-N-phenyl-3,4-bis(diphenylphosphino)pyrrolidine: an N-aryl pyrrolidine ligand for enantioselective transfer hydrogenation

The N-aryl pyrrolidine diphosphine (R,R)-N-phenyl-3,4-bis(diphenylphosphino)pyrrolidine was obtained from natural tartaric acid. Contrary to our preliminary expectations, this new chiral ligand proved to be less selective than the corresponding N-benzyl pyrrolidine diphosphine. An attempted explanat...

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Bibliographic Details
Main Author: Gonsalves, António Manuel d'Albuquerque Rocha (author)
Other Authors: Serra, Maria Elisa da Silva (author), Silva, Manuela Ramos (author), Beja, Ana Matos (author), Paixão, José António (author), Veiga, Luiz Alte da (author)
Format: article
Language:eng
Published: 2001
Subjects:
Transfer hydrogenation
Pyrrolidine diphosphine
Asymmetric catalysis
Five-membered chelate
Rhodium
Online Access:http://hdl.handle.net/10316/5223
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/5223
Description
Summary:The N-aryl pyrrolidine diphosphine (R,R)-N-phenyl-3,4-bis(diphenylphosphino)pyrrolidine was obtained from natural tartaric acid. Contrary to our preliminary expectations, this new chiral ligand proved to be less selective than the corresponding N-benzyl pyrrolidine diphosphine. An attempted explanation of the observed behaviour based on the stereochemistry of the ligand as shown by X-ray crystallography is presented.

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