Rotavirus stimulates release of serotonin (5-HT) from human enterochromaffin cells and activates brain structures involved in nausea and vomiting

Rotavirus (RV) is the major cause of severe gastroenteritis in young children. A virus-encoded enterotoxin, NSP4 is proposed to play a major role in causing RV diarrhoea but how RV can induce emesis, a hallmark of the illness, remains unresolved. In this study we have addressed the hypothesis that R...

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Bibliographic Details
Main Author: Hagbom, Marie (author)
Other Authors: Istrate, Claudia (author), Engblom, David (author), Karlsson, Thommie (author), Rodriguez-Diaz, Jesus (author), Buesa, Javier (author), Taylor, John A. (author), Loitto, Vesa Matti (author), Magnusson, Karl Eric (author), Ahlman, Håkan (author), Lundgren, Ove (author), Svensson, Lennart (author)
Format: article
Language:eng
Published: 2021
Subjects:
Immunology
Molecular Biology
Virology
SDG 3 - Good Health and Well-being
Online Access:http://hdl.handle.net/10362/117150
Country:Portugal
Oai:oai:run.unl.pt:10362/117150

Internet

http://hdl.handle.net/10362/117150

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