Dialkyl imidazolinones from alpha,alpha-dialkyl glycines

In recent years, our group has been involved in the use of the Ugi-Passerini reaction for the synthesis of several alpha,alpha-dialkylglycines. The C-terminal amide bond of the resulting Ugi adducts 1 proved to be very sensitive to TFA, cleaving readily by a mechanism involving an oxazolinium-type i...

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Bibliographic Details
Main Author: Costa, Susana P. G. (author)
Other Authors: Maia, Hernâni L. S. (author), Lima, Sílvia M. M. A. Pereira (author)
Format: conferenceObject
Language:eng
Published: 2003
Subjects:
Online Access:http://hdl.handle.net/1822/1931
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/1931