Reaction of naphthoquinones with substituted nitromethanes. Facile synthesis and antifungal activity of naphtho[2,3- d]isoxazole-4,9-diones

We report here a simple entry into naphtho[2,3-d]isoxazole-4,9-dione system containing a EWG in position 3 using the readily available 2,3-dichloro-1,4-naphthoquinone and nitromethyl derivatives in the presence of base. Antifungal activity of synthesised naphthoquinones was evaluated against ATCC an...

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Bibliographic Details
Main Author: Santos, Maria M. M. (author)
Other Authors: Faria, Natália (author), Iley, Jim (author), Coles, Simon J. (author), Hursthouse, Michael B. (author), Martins, M. Luz (author), Moreira, Rui (author)
Format: article
Language:eng
Published: 2011
Subjects:
Quinones
Isoxazoles
Heterocycles
Antifungal agents
Online Access:http://hdl.handle.net/10451/3852
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/3852

Internet

http://hdl.handle.net/10451/3852

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