Local and regional re-establishment of cellular immunity during curative antibiotherapy of murine Mycobacterium ulcerans infection

BACKGROUND: Buruli ulcer (BU) is a neglected necrotizing disease of the skin, subcutaneous tissue and bone, caused by Mycobacterium ulcerans. BU pathogenesis is associated with mycolactone, a lipidic exotoxin with cytotoxic and immunosuppressive properties. Since 2004, the World Health Organization...

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Bibliographic Details
Main Author: Martins, Teresa G. (author)
Other Authors: Gama, José B. (author), Fraga, Alexandra G. (author), Saraiva, Margarida (author), Silva, Manuel T. (author), Castro, António G. (author), Pedrosa, Jorge (author)
Format: article
Language:eng
Published: 2012
Subjects:
Buruli ulcer
Mycobacterium ulcerans
Antibiotics
Science & Technology
Online Access:http://hdl.handle.net/1822/21974
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/21974

Internet

http://hdl.handle.net/1822/21974

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