Quantifying next generation sequencing sample pre-processing bias in HIV-1 complete genome sequencing

Genetic analyses play a central role in infectious disease research. Massively parallelized “mechanical cloning” and sequencing technologies were quickly adopted by HIV researchers in order to broaden the understanding of the clinical importance of minor drug-resistant variants. These efforts have,...

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Bibliographic Details
Main Author: Vrancken, Bram (author)
Other Authors: Trovão, Nídia Sequeira (author), Baele, Guy (author), Van Wijngaerden, Eric (author), Vandamme, Anne Mieke (author), van Laethem, Kristel (author), Lemey, Philippe (author)
Format: article
Language:eng
Published: 2018
Subjects:
Full genome sequencing
HIV
NGS
Infectious Diseases
Virology
SDG 3 - Good Health and Well-being
Online Access:https://doi.org/10.3390/v8010012
Country:Portugal
Oai:oai:run.unl.pt:10362/36646

Internet

https://doi.org/10.3390/v8010012

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