Synthesis of novel benzofurocoumarin analogues and their anti-proliferative effect on human cancer cell lines

The synthesis of five new tetracyclic benzofurocoumarin (benzopsoralen) analogues is described. Their inhibitory effects on the growth of three human tumour cell lines (MDA MB 231 (breast adenocarcinoma), HeLa (cervix adenocarcinoma) and TCC-SUP (bladder transitional cell carcinoma)) were evaluated,...

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Detalhes bibliográficos
Autor principal: Francisco, Carla S. (author)
Outros Autores: Rodrigues, L. R. (author), Cerqueira, N. M. F. S. A. (author), Campos, Ana M. F. Oliveira (author), Rodrigues, Lígia M. (author)
Formato: article
Idioma:eng
Publicado em: 2012
Assuntos:
Benzofurocoumarins;
Benzopsoralen analogues
Antitumour activity
Docking
Computational studies
Antitumor activity
Science & Technology
Texto completo:http://hdl.handle.net/1822/16410
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/16410

Texto Completo

http://hdl.handle.net/1822/16410

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