Synthesis of novel benzofurocoumarin analogues and their anti-proliferative effect on human cancer cell lines

The synthesis of five new tetracyclic benzofurocoumarin (benzopsoralen) analogues is described. Their inhibitory effects on the growth of three human tumour cell lines (MDA MB 231 (breast adenocarcinoma), HeLa (cervix adenocarcinoma) and TCC-SUP (bladder transitional cell carcinoma)) were evaluated,...

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Bibliographic Details
Main Author: Francisco, Carla S. (author)
Other Authors: Rodrigues, L. R. (author), Cerqueira, N. M. F. S. A. (author), Campos, Ana M. F. Oliveira (author), Rodrigues, Lígia M. (author)
Format: article
Language:eng
Published: 2012
Subjects:
Benzofurocoumarins;
Benzopsoralen analogues
Antitumour activity
Docking
Computational studies
Antitumor activity
Science & Technology
Online Access:http://hdl.handle.net/1822/16410
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/16410

Internet

http://hdl.handle.net/1822/16410

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