Coenzyme Q10 deficiency in mitochondrial DNA depletion syndromes

We evaluated coenzyme Q10 (CoQ) levels in patients studied under suspicion of mitochondrial DNA depletion syndromes (MDS) (n = 39). CoQ levels were quantified by HPLC, and the percentage of mtDNA depletion by quantitative real-time PCR. A high percentage of MDS patients presented with CoQ deficiency...

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Bibliographic Details
Main Author: Montero, Raquel (author)
Other Authors: Grazina, Manuela (author), López-Gallardo, Ester (author), Montoya, Julio (author), Briones, Paz (author), Navarro-Sastre, Aleix (author), Land, John M. (author), Hargreaves, Iain P. (author), Artuch, Rafael (author), O'Callaghan, Maria del Mar (author), Jou, Cristina (author), Jimenez, Cecilia (author), Buján, Nuria (author), Pineda, Mercè (author), García-Cazorla, Angels (author), Nascimento, Andrés (author), Perez-Dueñas, Belen (author), Ruiz-Pesini, Eduardo (author), Fratter, Carl (author), Salviati, Leonardo (author), Simões, Marta (author), Mendes, Cândida (author), Santos, Maria João (author), Diogo, Luísa (author), Garcia, Paula (author), Navas, Plácido (author)
Format: article
Language:eng
Published: 2013
Subjects:
Mitochondrial DNA depletion syndrome
Coenzyme Q10 deficiency
Mitochondrial disorders
Online Access:http://hdl.handle.net/10316/27281
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/27281

Internet

http://hdl.handle.net/10316/27281

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