Tamoxifen Inhibits Induction of the Mitochondrial Permeability Transition by Ca2+and Inorganic Phosphate

Tamoxifen (TAM) is a synthetic, nonsteroidal antiestrogenic agent that is widely prescribed in the treatment of estrogen-dependent neoplasias, including breast cancer. The mechanism of action has yet to be defined, but likely is independent of estrogen receptor binding. In light of its high lipophil...

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Detalhes bibliográficos
Autor principal: Custódio, José B. A. (author)
Outros Autores: Moreno, António J. M. (author), Wallace, Kendall B. (author)
Formato: article
Idioma:eng
Publicado em: 1998
Assuntos:
Texto completo:http://hdl.handle.net/10316/5825
País:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/5825