Signalling mechanisms that regulate metabolic profile and autophagy of acute myeloid leukaemia cells

Acute myeloid leukaemia (AML) comprises a heterogeneous group of hematologic neoplasms characterized by diverse combinations of genetic, phenotypic and clinical features representing a major challenge for the development of targeted therapies. Metabolic reprogramming, mainly driven by deregulation o...

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Bibliographic Details
Main Author: Pereira, Olga (author)
Other Authors: Teixeira, Alexandra (author), Marques, Maria Belém Sousa Sampaio (author), Castro, Isabel (author), Girão, Henrique (author), Ludovico, Paula (author)
Format: article
Language:eng
Published: 2018
Subjects:
acute myeloid leukaemia
autophagy
energetic metabolism
glycolysis
mitochondrial oxidative phosphorylation
nutrient-sensing pathways
Ciências Médicas::Medicina Básica
Science & Technology
Online Access:http://hdl.handle.net/1822/58061
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/58061

Internet

http://hdl.handle.net/1822/58061

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