NudE regulates dynein at kinetochores but is dispensable for other dynein functions in the C. elegans early embryo

In mitosis, themolecular motor dynein is recruited to kinetochores by the Rod-Zw10-Zwilch complex (RZZ) and Spindly to control spindle assembly checkpoint (SAC) signaling and microtubule attachment. How the ubiquitous dynein co-factors Lis1 and NudE contribute to these functions remains poorly under...

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Detalhes bibliográficos
Autor principal: Simões, PA (author)
Outros Autores: Celestino, R (author), Carvalho, AX (author), Gassmann, R (author)
Formato: article
Idioma:eng
Publicado em: 2018
Texto completo:https://hdl.handle.net/10216/127046
País:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/127046