NudE regulates dynein at kinetochores but is dispensable for other dynein functions in the C. elegans early embryo

In mitosis, themolecular motor dynein is recruited to kinetochores by the Rod-Zw10-Zwilch complex (RZZ) and Spindly to control spindle assembly checkpoint (SAC) signaling and microtubule attachment. How the ubiquitous dynein co-factors Lis1 and NudE contribute to these functions remains poorly under...

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Bibliographic Details
Main Author: Simões, PA (author)
Other Authors: Celestino, R (author), Carvalho, AX (author), Gassmann, R (author)
Format: article
Language:eng
Published: 2018
Online Access:https://hdl.handle.net/10216/127046
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/127046