Mitochondria dysfunction of Alzheimer's disease cybrids enhances Aβ toxicity

Alzheimer's disease (AD) brain reveals high rates of oxygen consumption and oxidative stress, altered antioxidant defences, increased oxidized polyunsaturated fatty acids, and elevated transition metal ions. Mitochondrial dysfunction in AD is perhaps relevant to these observations, as such may...

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Bibliographic Details
Main Author: Cardoso, Sandra M. (author)
Other Authors: Santana, Isabel (author), Swerdlow, Russell H. (author), Oliveira, Catarina R. (author)
Format: article
Language:eng
Published: 2004
Online Access:http://hdl.handle.net/10316/8427
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/8427