Mitochondria dysfunction of Alzheimer's disease cybrids enhances Aβ toxicity

Alzheimer's disease (AD) brain reveals high rates of oxygen consumption and oxidative stress, altered antioxidant defences, increased oxidized polyunsaturated fatty acids, and elevated transition metal ions. Mitochondrial dysfunction in AD is perhaps relevant to these observations, as such may...

ver descrição completa

Detalhes bibliográficos
Autor principal: Cardoso, Sandra M. (author)
Outros Autores: Santana, Isabel (author), Swerdlow, Russell H. (author), Oliveira, Catarina R. (author)
Formato: article
Idioma:eng
Publicado em: 2004
Texto completo:http://hdl.handle.net/10316/8427
País:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/8427