Contribution of red cell mass and ugt1a1 alleles in serum bilirubin levels of the portuguese population

Hepatic glucuronization of insoluble bilirubin is catalyzed by isoenzyme 1A1 of UDP-glucuronosyltransferase (UGT1A1), which is essential for efficient biliary excretion of bilirubin. The main cause of Gilbert syndrome (GS) in all populations studied to date is a TA duplication [(TA)7 allele] in the...

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Detalhes bibliográficos
Autor principal: Rodrigues, Carina (author)
Outros Autores: Costa, Elísio (author), Santos-Silva, Alice (author), Bronze-da-Rocha, Elsa (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2012
Assuntos:
Texto completo:http://hdl.handle.net/10198/7088
País:Portugal
Oai:oai:bibliotecadigital.ipb.pt:10198/7088