Mycobacterium ulcerans Triggers T-cell immunity followed by local and regional but not systemic immunosuppression

Buruli ulcer (BU) is a neglected infectious disease caused by Mycobacterium ulcerans, characterized by necrotic cutaneous lesions induced by the exotoxin mycolactone. Despite evidence of Th1-mediated protective immunity, M. ulcerans infection has been associated with systemic immunosuppression. We s...

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Detalhes bibliográficos
Autor principal: Fraga, Alexandra G. (author)
Outros Autores: Cruz, Andrea (author), Martins, Teresa G. (author), Torrado, Egídio (author), Saraiva, Margarida (author), Pereira, Daniela Maria Ramos (author), Meyers, Wayne M. (author), Portaels, Françoise (author), Silva, Manuel T. (author), Castro, António G. (author), Pedrosa, Jorge (author)
Formato: article
Idioma:eng
Publicado em: 2011
Assuntos:
Buruli ulcer
Science & Technology
Texto completo:http://hdl.handle.net/1822/18746
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/18746

Texto Completo

http://hdl.handle.net/1822/18746

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