Alternative splicing of tumour-related rac1b is regulated by upstream signalling pathways
The small GTPase Rac1 regulates signalling pathways controlling actin-dependent cell motility as well as gene transcription. Analternative splicing variant Rac1b is overexpressed in a subset of colorectal tumours and cooperates with mutant B-Raf to sustain tumour cellviability. The alternative splic...
| Autor principal: | |
|---|---|
| Outros Autores: | , |
| Formato: | conferenceObject |
| Idioma: | eng |
| Publicado em: |
2012
|
| Assuntos: | |
| Texto completo: | http://hdl.handle.net/10400.18/1024 |
| País: | Portugal |
| Oai: | oai:repositorio.insa.pt:10400.18/1024 |