Alternative splicing of tumour-related rac1b is regulated by upstream signalling pathways

The small GTPase Rac1 regulates signalling pathways controlling actin-dependent cell motility as well as gene transcription. Analternative splicing variant Rac1b is overexpressed in a subset of colorectal tumours and cooperates with mutant B-Raf to sustain tumour cellviability. The alternative splic...

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Bibliographic Details
Main Author: Gonçalves, Vânia (author)
Other Authors: Matos, Paulo (author), Jordan, Peter (author)
Format: conferenceObject
Language:eng
Published: 2012
Subjects:
Vias de Transdução de Sinal e Patologias Associadas
Rac1b
Splicing Alternativo
Cancro Colorectal
Online Access:http://hdl.handle.net/10400.18/1024
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/1024

Internet

http://hdl.handle.net/10400.18/1024

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