Identification of Li+ binding sites and the effect of Li+ treatment on phospholipid composition in human neuroblastoma cells: a 7Li and 31P NMR study

Li+ binding in subcellular fractions of human neuroblastoma SH-SY5Y cells was investigated using 7Li NMR spin-lattice (T1) and spin-spin (T2) relaxation measurements, as the T1/T2 ratio is a sensitive parameter of Li+ binding. The majority of Li+ binding occurred in the plasma membrane, microsomes,...

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Bibliographic Details
Main Author: Layden, Brian T. (author)
Other Authors: Abukhdeir, Abde M. (author), Malarkey, Christopher (author), Oriti, Lisa A. (author), Salah, Wajeeh (author), Stigler, Claire (author), Geraldes, Carlos F. G. C. (author), Freitas, Duarte Mota (author)
Format: article
Language:eng
Published: 2005
Subjects:
Cell membrane
Cytosol
Lithium
Mitochondria
Phospholipid
Online Access:http://hdl.handle.net/10316/3863
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/3863

Internet

http://hdl.handle.net/10316/3863

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