pH homeostasis links the nutrient sensing PKA/TORC1/Sch9 ménage-à-trois to stress tolerance and longevity

The plasma membrane H+-ATPase Pma1 and the vacuolar V-ATPase act in close harmony to tightly control pH homeostasis, which is essential for a vast number of physiological processes. As these main two regulators of pH are responsive to the nutritional status of the cell, it seems evident that pH home...

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Bibliographic Details
Main Author: Deprez, Marie-Anne (author)
Other Authors: Eskes, Elja (author), Wilms, Tobias (author), Ludovico, Paula (author), Winderickx, Joris (author)
Format: article
Language:eng
Published: 2018
Subjects:
Yeast
Ageing
Longevity
pH
V-ATPase
Pma1
PKA
TORC1
Sch9
Ciências Médicas::Medicina Básica
Science & Technology
Online Access:http://hdl.handle.net/1822/58049
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/58049

Internet

http://hdl.handle.net/1822/58049

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