The soluble form of HFE protein regulates hephaestin mRNA expression in the duodenum through an endocytosis-dependent mechanism

Dietary iron absorption regulation is one of the key steps for the maintenance of the body iron homeostasis. HFE gene expression undergoes a complex post-transcriptional alternative splicing mechanism through which two alternative transcripts are originated and translated to a soluble HFE protein is...

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Bibliographic Details
Main Author: Silva, Bruno (author)
Other Authors: Ferreira, Joana (author), Santos, Vera (author), Baldaia, Cilénia (author), Serejo, Fátima (author), Faustino, Paula (author)
Format: article
Language:eng
Published: 2015
Subjects:
HFE
Metabolismo do Ferro
Endocitose
Duodeno
Doenças Genéticas
Alternative Splicing
Iron Metabolism
Enterocyte
Iron Absorption
Macrophage
Endocytosis
Online Access:http://hdl.handle.net/10400.18/2365
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/2365

Internet

http://hdl.handle.net/10400.18/2365

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