Targeting tumour-related alternative splice variant RAC1B with anti-sense oligonucleotides

Over 90% of human protein coding genes are able to generate more than one transcript due to alternative splicing. In cancer, certain alternative splicing variants are frequently overexpressed and contribute to tumour progression and aggressiveness. This is well illustrated by RAC1B, a variant of the...

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Detalhes bibliográficos
Autor principal: Bessa, Cláudia (author)
Outros Autores: Gonçalves, Vânia (author), Jordan, Peter (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2022
Assuntos:
Texto completo:http://hdl.handle.net/10400.18/7971
País:Portugal
Oai:oai:repositorio.insa.pt:10400.18/7971