Targeting tumour-related alternative splice variant RAC1B with anti-sense oligonucleotides

Over 90% of human protein coding genes are able to generate more than one transcript due to alternative splicing. In cancer, certain alternative splicing variants are frequently overexpressed and contribute to tumour progression and aggressiveness. This is well illustrated by RAC1B, a variant of the...

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Bibliographic Details
Main Author: Bessa, Cláudia (author)
Other Authors: Gonçalves, Vânia (author), Jordan, Peter (author)
Format: conferenceObject
Language:eng
Published: 2022
Subjects:
Online Access:http://hdl.handle.net/10400.18/7971
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/7971