Analysis of the divergences in the nonsense-mediated mRNA decay mechanism among two globin transcripts highly conserved
Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that recognizes and selectively degrades mRNAs carrying premature termination codons (PTCs, or nonsense codons), which has been highly conserved during evolution. Knowing that human a- and b-globin genes descend from a common ancestral, th...
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Format: | conferenceObject |
Language: | eng |
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2012
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Online Access: | http://hdl.handle.net/10400.18/893 |
Country: | Portugal |
Oai: | oai:repositorio.insa.pt:10400.18/893 |