Analysis of the divergences in the nonsense-mediated mRNA decay mechanism among two globin transcripts highly conserved

Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that recognizes and selectively degrades mRNAs carrying premature termination codons (PTCs, or nonsense codons), which has been highly conserved during evolution. Knowing that human a- and b-globin genes descend from a common ancestral, th...

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Bibliographic Details
Main Author: Pereira, Francisco JC (author)
Other Authors: Romão, Luísa (author)
Format: conferenceObject
Language:eng
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/10400.18/893
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/893