Paediatric cerebral vasculopathy in sickle cell anaemia: contribution of genetic modifiers

Sickle cell anaemia (SCA) arises from homozygosity for the mutation c.20A>T in the HBB gene. However, it shows a multifactorial-like behaviour with high heterogeneity of clinical features. Cerebral vasculopathy (CVA), namely paediatric ischemic stroke, is one of its most devastating consequences....

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Bibliographic Details
Main Author: Silva, Marisa (author)
Other Authors: Vargas, Sofia (author), Coelho, Andreia (author), Mendonça, Joana (author), Vieira, Luís (author), Kjollerstrom, Paula (author), Maia, Raquel (author), Silva, Rita (author), Dias, Alexandra (author), Ferreira, Teresa (author), Morais, Anabela (author), Mota Soares, Isabel (author), Lavinha, João (author), Faustino, Paula (author)
Format: conferenceObject
Language:eng
Published: 2020
Subjects:
Sickle Cell Anaemia
Cerebral Vasculopathy
Genetic Modifiers
Hemoglobinopatias
Anemia
VCAM1
Vasculopatia cerebral
Modificadores genéticos
Medicina personalizada
Doenças Genéticas
Doenças Raras
Drepanocitose
Anemia das Células Falciformes
Online Access:http://hdl.handle.net/10400.18/6731
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/6731

Internet

http://hdl.handle.net/10400.18/6731

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