Microglial innate memory and epigenetic reprogramming in neurological disorders

Microglia are myeloid-derived cells recognized as brain-resident macrophages. They act as the first and main line of immune defense in the central nervous system (CNS). Microglia have high phenotypic plasticity and are essential for regulating healthy brain homeostasis, and their dysregulation under...

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Bibliographic Details
Main Author: Martins-Ferreira, Ricardo (author)
Other Authors: Leal, Bárbara (author), Costa, Paulo (author), Ballestar, Esteban (author)
Format: article
Language:eng
Published: 2021
Subjects:
Microglia
DNA Methylation
Neurological Diseases
Epigenetics
Innate Immunity
Histone Modifications
Innate Immune Memory
Doenças Genéticas
Online Access:http://hdl.handle.net/10400.18/7605
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/7605

Internet

http://hdl.handle.net/10400.18/7605

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