The role of Ube3a in neuronal development
Angelman syndrome (AS) is a genetic disorder characterized by paternal imprinting and maternal deletion of Ube3a. Therefore AS patients have reduced levels of expression of Ube3a in several regions of the brain including the hippocampus and cerebellum. AS patients have motor impairment, mental retar...
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| Formato: | masterThesis |
| Idioma: | eng |
| Publicado em: |
2023
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| Texto completo: | http://hdl.handle.net/10773/33367 |
| País: | Portugal |
| Oai: | oai:ria.ua.pt:10773/33367 |