Study of the metabolome and muscle strength measures for the characterization of patients with myotonic dystrophy type 1

Myotonic dystrophy type 1 (DM1) is an autosomal dominant hereditary disease caused by an alteration leading to an abnormal expansion of unstable repetitions of CTG in the 3’ untranslated region of Myotonic Dystrophy Protein Kinase (DMPK) gene. DM1 is characterized by myotonia, progressive distal mus...

Full description

Bibliographic Details
Main Author: Mateus, Tiago Duarte Cordeiro (author)
Format: masterThesis
Language:eng
Published: 2023
Subjects:
Myotonic dystrophy type 1
DMPK
Metabolic syndrome
Dyslipidemia
Lipin
Insulin resistance
Metabolome profile
ATR-FTIR spectroscopy
Multivariate analysis
Outcome measures
Muscle strength
Cardiac muscle
Skeletal muscle
Respiratory muscle
Online Access:http://hdl.handle.net/10773/30819
Country:Portugal
Oai:oai:ria.ua.pt:10773/30819

Internet

http://hdl.handle.net/10773/30819

Similar Items