Rapid determination of anti-tuberculosis drug resistance from whole-genome sequences

Mycobacterium tuberculosis drug resistance (DR) challenges effective tuberculosis disease control. Current molecular tests examine limited numbers of mutations, and although whole genome sequencing approaches could fully characterise DR, data complexity has restricted their clinical application. A l...

Full description

Bibliographic Details
Main Author: Coll, Francesc (author)
Other Authors: McNerney, Ruth (author), Preston, Mark D. (author), Guerra-Assunção, José Afonso (author), Warry, Andrew (author), Hill-Cawthorne, Grant (author), Mallard, Kim (author), Nair, Mridul (author), Miranda, Anabela (author), Alves, Adriana (author), Perdigão, João (author), Viveiros, Miguel (author), Portugal, Isabel (author), Hasan, Zahra (author), Hasan, Rumina (author), Glynn, Judith R. (author), Martin, Nigel (author), Pain, Arnab (author), Clark, Taane G. (author)
Format: article
Language:eng
Published: 2016
Subjects:
Online Access:http://hdl.handle.net/10400.18/3554
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/3554