New di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series: Synthesis, growth inhibitory activity on human tumor cell lines and non-tumor cells, effects on cell cycle and on programmed cell death

New fluorinated and methoxylated di(hetero)arylethers and di(hetero)arylamines were prepared functionalizing the 7-position of the thieno[3,2-b]pyridine, using copper (C–O) or palladium (C–N) catalyzed couplings, respectively, of the 7-bromothieno[3,2-b]pyridine, also prepared, with ortho, meta and...

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Bibliographic Details
Main Author: Queiroz, Maria João R.P. (author)
Other Authors: Peixoto, Daniela (author), Calhelha, Ricardo C. (author), Soares, Pedro (author), Santos, Tiago (author), Lima, Raquel T. (author), Campos, Joana F. (author), Abreu, Rui M.V. (author), Ferreira, Isabel C.F.R. (author), Vasconcelos, M. Helena (author)
Format: article
Language:eng
Published: 2014
Subjects:
Di(hetero)arylethers
Di(hetero)arylamines
Thieno[3,2-b]pyridines
Metal-catalyzed couplings
Tumor and nontumor cells growth inhibition
Cell cycle analysis and cell death
Online Access:http://hdl.handle.net/10198/9177
Country:Portugal
Oai:oai:bibliotecadigital.ipb.pt:10198/9177

Internet

http://hdl.handle.net/10198/9177

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