Role of CFTR in Epithelial Differentiation by Functional Genomics

Cystic Fibrosis (CF) is caused by mutations in the CFTR gene. The relationship between CFTR and differentiation has been firmly documented. However, the mechanisms that regulate this relationship are still unclear. The aim of this work was to further characterize the differentiation defect in CF and...

Full description

Bibliographic Details
Main Author: Sousa, Luís Miguel dos Santos (author)
Format: doctoralThesis
Language:eng
Published: 2021
Subjects:
Fibrose Quística
KLF4
Diferenciação epitelial
AKT
EMT
Cystic Fibrosis
Epithelial differentiation
AKT signalling
Domínio/Área Científica::Ciências Naturais::Ciências Biológicas
Online Access:http://hdl.handle.net/10451/48522
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/48522

Internet

http://hdl.handle.net/10451/48522

Similar Items