The expression of the soluble HFE corresponding transcript is up-regulated by intracellular iron and inhibits iron absorption in a duodenal cell model

Background and aims: Dietary iron absorption regulation is a key-step for the maintenance of body iron homeostasis. Besides the HFE full-length protein, the HFE gene codes for alternative splicing variants responsible for the synthesis of a soluble form of HFE protein (sHFE). Here we aimed to determ...

Full description

Bibliographic Details
Main Author: Silva, Bruno (author)
Other Authors: Ferreira, Joana (author), Santos, Vera (author), Baldaia, Cilénia (author), Serejo, Fátima (author), Faustino, Paula (author)
Format: conferenceObject
Language:eng
Published: 2014
Subjects:
Metabolismo do Ferro
HFE
Hemocromatose Hereditária
Doenças Genéticas
Online Access:http://hdl.handle.net/10400.18/2277
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/2277

Internet

http://hdl.handle.net/10400.18/2277

Similar Items