Chiral resolution and enantioselectivity of synthetic cathinones: A brief review

Chiral discrimination has become one of the most important fields in analytical and medicinal chemistry, and forensic toxicology. The enantiomers may have different binding to proteins that may lead to many pharmacological and toxicological differences between them, including kinetic (at the absorpt...

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Bibliographic Details
Main Author: Silva B. (author)
Other Authors: Fernandes C. (author), de Pinho P.G. (author), Remião F. (author)
Format: article
Language:eng
Published: 2018
Subjects:
4' methylmethcathinone
cathinone
drug metabolite
methylenedioxypyrovalerone
neurotransmitter
unclassified drug
alkaloid
psychotropic agent
animal behavior
chiral chromatography
chirality
enantiomer
enantioselectivity
human
hyperthermic effect
liver cell
liver toxicity
metabolite
mouse
nonhuman
primary cell culture
rat
Review
synthesis
Turbellaria
animal
drug dependence
isomerism
procedures
structure activity relation
substance abuse
Alkaloids
Animals
Humans
Isomerism
Psychotropic Drugs
Structure-Activity Relationship
Substance Abuse Detection
Substance-Related Disorders
Online Access:https://hdl.handle.net/10216/120448
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/120448

Internet

https://hdl.handle.net/10216/120448

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