Epidermal growth factor receptor inhibitory activity of new potential antitumor di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series
Thienopyridine skeleton has been reported as having interesting biological activity, namely as antitumorals [1] and antiangiogenics [2]. The Epidermal Growth Factor Receptor (EGFR) exists in the cell surface and is activated by binding its specific ligands. The inhibition of its intracellular tyrosi...
| Main Author: | |
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| Other Authors: | , , , , |
| Format: | conferenceObject |
| Language: | eng |
| Published: |
2014
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| Online Access: | http://hdl.handle.net/10198/9396 |
| Country: | Portugal |
| Oai: | oai:bibliotecadigital.ipb.pt:10198/9396 |