Production and characterization of recombinant Aliivibrio fischeri L-Asparaginase with low L-Glutamine affinity: a potential antileukemic drug obtained by genetic engineering

L-Asparaginase has been successfully applied in the treatment of lymphoid malignancies. Some limitations in the use of the commercial preparations of this drug include several side effects that may be correlated to L-Glutaminase activity, as immunosuppressive effects (Castro et al., 2021). The objec...

Full description

Bibliographic Details
Main Author: Bento, Heitor B. S. (author)
Other Authors: Paiva, Gabriela B. (author), Pedrolli, Danielle B. (author), Tavares, Ana P. M. (author), Santos-Ebinuma, Valéria (author)
Format: conferenceObject
Language:eng
Published: 2022
Subjects:
Online Access:http://hdl.handle.net/10773/33134
Country:Portugal
Oai:oai:ria.ua.pt:10773/33134