Posterior Reversible Encephalopathy Syndrome: A Case of Hypercalcemia

Posterior reversible encephalopathy syndrome is an encephalopathy that can be clinically characterized by headache, altered mental status and/or seizures. Neuroimaging demonstrates usually reversible bilateral subcortical vasogenic occipital-parietal edema. Exact pathophysiology remains unclear but...

Full description

Bibliographic Details
Main Author: Ponciano, Ana (author)
Other Authors: Vieira, Vera (author), Leite, José (author), Fernandes, Célio (author)
Format: article
Language:eng
Published: 2018
Subjects:
Online Access:https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/9714
Country:Portugal
Oai:oai:ojs.www.actamedicaportuguesa.com:article/9714
Description
Summary:Posterior reversible encephalopathy syndrome is an encephalopathy that can be clinically characterized by headache, altered mental status and/or seizures. Neuroimaging demonstrates usually reversible bilateral subcortical vasogenic occipital-parietal edema. Exact pathophysiology remains unclear but is commonly associated with hypertension, renal failure, sepsis and use of immunosuppressive therapy. Its development in the setting of severe hypercalcemia is extremely rare. The authors report a case of posterior reversible encephalopathy syndrome in a normotensive patient with severe hypercalcemia as the only identifiable cause.