Comparison of the changes in adenine nucleotides of rat liver mitochondria induced by tamoxifen and 4-hydroxytamoxifen

The antiestrogen tamoxifen (TAM) inhibits the growth of different estrogen receptor (ER)-negative cells. Recently, multiple effects of TAM on mitochondrial bioenergetic functions have been pointed to explain its ER-independent cell death mechanisms. We have shown that TAM and its major active metabo...

Full description

Bibliographic Details
Main Author: Cardoso, Carla M. P. (author)
Other Authors: Moreno, António J. M. (author), Almeida, Leonor M. (author), Custódio, José B. A. (author)
Format: article
Language:eng
Published: 2003
Subjects:
4-Hydroxytamoxifen
Mitochondrial energetics
Mitochondrial adenine nucleotides
Phosphate carrier
Adenine nucleotide translocase
Tamoxifen
Online Access:http://hdl.handle.net/10316/5778
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/5778

Internet

http://hdl.handle.net/10316/5778

Similar Items