Comparison of the changes in adenine nucleotides of rat liver mitochondria induced by tamoxifen and 4-hydroxytamoxifen

The antiestrogen tamoxifen (TAM) inhibits the growth of different estrogen receptor (ER)-negative cells. Recently, multiple effects of TAM on mitochondrial bioenergetic functions have been pointed to explain its ER-independent cell death mechanisms. We have shown that TAM and its major active metabo...

ver descrição completa

Detalhes bibliográficos
Autor principal: Cardoso, Carla M. P. (author)
Outros Autores: Moreno, António J. M. (author), Almeida, Leonor M. (author), Custódio, José B. A. (author)
Formato: article
Idioma:eng
Publicado em: 2003
Assuntos:
4-Hydroxytamoxifen
Mitochondrial energetics
Mitochondrial adenine nucleotides
Phosphate carrier
Adenine nucleotide translocase
Tamoxifen
Texto completo:http://hdl.handle.net/10316/5778
País:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/5778

Texto Completo

http://hdl.handle.net/10316/5778

Registos relacionados