Transthyretin proteins regulate angiogenesis by conferring different molecular identities to endothelial cells

* This work was supported by Fundação para a Ciencia e Tecnologia Grant PIC/IC/83062/2007. The data reported in this paper have been deposited in the Gene Expression Omnibus (GEO) database,www.ncbi.nlm.nih.gov/geo (accession no. GSE44856). Supported by Fundação para a Ciencia e Tecnologia (FCT) Fell...

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Bibliographic Details
Main Author: Nunes, R.J. (author)
Other Authors: De Oliveira, P. (author), Lages, A. (author), Becker, J.D. (author), Marcelino, P. (author), Barroso, E. (author), Perdigoto, R. (author), Kelly, J.W. (author), Quintas, A. (author), Santos, S.C.R. (author)
Format: article
Language:eng
Published: 2018
Subjects:
Biological effects
Disease symptoms
Familial amyloidotic polyneuropathy
Hepatic artery
Liver transplantation
Molecular identities
Risk factors
Transthyretin
Amino acids
Blood vessels
Cell death
Disease control
Diseases
Endothelial cells
Proteins
Liver
prealbumin
antiangiogenic activity
apoptosis
article
biological activity
cell migration
cell survival
controlled study
down regulation
endothelium cell
gene expression regulation
human
human cell
nucleotide sequence
priority journal
protein synthesis
Angiogenesis
Endothelial Cell
Familial Amyloidotic Polyneuropathy
Gene Expression
Microarray
Vascular Biology
Allografts
Amino Acid Substitution
Amyloid Neuropathies, Familial
Apoptosis
Cell Survival
Cells, Cultured
Gene Expression Regulation
Human Umbilical Vein Endothelial Cells
Humans
Liver Transplantation
Mutation, Missense
Neovascularization, Physiologic
Prealbumin
Thrombosis
SDG 3 - Good Health and Well-being
Online Access:https://doi.org/10.1074/jbc.M113.469858
Country:Portugal
Oai:oai:run.unl.pt:10362/53314
Description
Summary:* This work was supported by Fundação para a Ciencia e Tecnologia Grant PIC/IC/83062/2007. The data reported in this paper have been deposited in the Gene Expression Omnibus (GEO) database,www.ncbi.nlm.nih.gov/geo (accession no. GSE44856). Supported by Fundação para a Ciencia e Tecnologia (FCT) Fellowship SFRH/BPD/43482/2008. 2 To whom correspondence should be addressed: Angiogenesis Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Av. Professor Egas Moniz, 1649-028 Lisbon, Portugal. Tel.: 351-217999411; Fax: 351-217999412; E-mail: sconstantino@fm.ul.pt.

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