Unraveling the role of internal ribosome entry site (IRES) mediated translation in human UPF1 expression and function

Up-frameshift 1 (UPF1) is the key factor in nonsense-mediated mRNA decay (NMD, a mechanism that degrades transcripts carrying premature translation termination codons. Besides its role in NMD, UPF1 has also a role in other mechanisms, such as cell cycle progression, being crucial for the G1/S transi...

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Bibliographic Details
Main Author: Lacerda, Rafaela (author)
Other Authors: Menezes, Juliane (author), Romão, Luísa (author)
Format: conferenceObject
Language:eng
Published: 2021
Subjects:
Online Access:http://hdl.handle.net/10400.18/8142
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/8142