Unraveling the role of internal ribosome entry site (IRES) mediated translation in human UPF1 expression and function
Up-frameshift 1 (UPF1) is the key factor in nonsense-mediated mRNA decay (NMD, a mechanism that degrades transcripts carrying premature translation termination codons. Besides its role in NMD, UPF1 has also a role in other mechanisms, such as cell cycle progression, being crucial for the G1/S transi...
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Other Authors: | , |
Format: | conferenceObject |
Language: | eng |
Published: |
2021
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Subjects: | |
Online Access: | http://hdl.handle.net/10400.18/8142 |
Country: | Portugal |
Oai: | oai:repositorio.insa.pt:10400.18/8142 |