Hydrodynamics of a three-phase airlift reactor with an enlarged separator : application to high cell density systems

The hydrodynamic study of a three-phase airlift reactor with an enlarged head zone was carried out. Effects of gas-solid-liquid separator design and riser to downcomer cross-sectional area using different lengths and diameters of the draft tube were investigated. Ca-alginate beads with entrapped yea...

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Detalhes bibliográficos
Autor principal: Klein, Jaroslav (author)
Outros Autores: Vicente, A. A. (author), Teixeira, J. A. (author)
Formato: article
Idioma:eng
Publicado em: 2003
Assuntos:
Texto completo:http://hdl.handle.net/1822/1692
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/1692
Descrição
Resumo:The hydrodynamic study of a three-phase airlift reactor with an enlarged head zone was carried out. Effects of gas-solid-liquid separator design and riser to downcomer cross-sectional area using different lengths and diameters of the draft tube were investigated. Ca-alginate beads with entrapped yeast biomass at different loadings up to 21 % (v/v) were used in order to mimic the solid phase of conventional high cell density systems. The main hydrodynamic parameters – liquid circulation velocity, gas and solids holdups in all reactor sections have been measured and experimental values were satisfactorily predicted using an appropriate three-phase model. The results of this study may beapplied to suggest the optimal design (in terms of hydrodynamic behaviour) of a batch/continuous three-phase ALR for high cell density fermentations.